Enhancing chemoimmunotherapy for colorectal cancer with paclitaxel and alantolactone via CD44-Targeted nanoparticles: A STAT3 signaling pathway modulation approach

Chemoimmunotherapy has the potential to enhance chemotherapy and modulate the immunosuppressive tumor microenvironment by activating immunogenic cell death (ICD), making it a promising strategy for clinical application.Alantolactone (A) was found to augment the anticancer efficacy of paclitaxel (P) at a molar ratio of 1:0.5 (P:A) through induction

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HEPATIC STEATOSIS ASSESSMENT: a comparative study between surgeon evaluation and forward histopathologic findings

Context Liver transplantation is one of the last viable resources for patients with end-stage liver disease.Many strategies are been used to improve the number of available organs and overcome waiting list delay.However, hepatic steatosis is one of the mainly concerns when organs are consider to transplantation due to it is importance as a risk fac

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